2025

Falahkheirkhah, K., Mukherjee, S., Yeh, K., Cheville, J. and Bhargava, R., “Comprehensive digital chemical pathology using stimulated Raman scattering”. In Advanced Chemical Microscopy for Life Science and Translational Medicine 2025 (p. PC133320R). SPIE. (2025).
Paper | DOI: 10.1117/12.3043543

Liu, Y.T., Yeh, K., Confer, M.P., Sharma, I., Falahkheirkhah, K., Orr, A.C., Ho, R.J., Tamonis, M. and Bhargava, R., “Designing software solutions for infrared chemical imaging and digital pathology”. In Imaging, Manipulation, and Analysis of Biomolecules, Cells, and Tissues XXIII (p. PC133230M). SPIE. (2025).
Paper | DOI: 10.1117/12.3042353

Ho, R.J., Yeh, K. and Bhargava, R., “2025, March. “Polarization characterization and validation of laser-based vibrational circular dichroism spectroscopy using digitally referenced detection”. In Multiscale Imaging and Spectroscopy VI (p. PC133270F). SPIE. (2025).
Paper | DOI: 10.1117/12.3041288

Yeh, K.L., Falahkheirkhah, K., Liu, Y.T., Ho, R.J., Sharma, I., Confer, M.P., Orr, A.C., Tamonis, M. and Bhargava, R., “Translational efforts for digital chemical pathology with infrared laser scanning microscopy”. In Advanced Chemical Microscopy for Life Science and Translational Medicine 2025 (p. PC133320P). SPIE. (2025).
Paper | DOI: 10.1117/12.3043508

Hur, S.W., Sengupta, S., Kwon, M., Manoharaan, R., Anastasio, M. and Bhargava, R., “Single-shot quantitative phase gradient microscopy using physics-based untrained neural network phase retrieval”. In Quantitative Phase Imaging XI (Vol. 13329, pp. 12-15). SPIE. (2025).
Paper | DOI: 10.1117/12.3043703

Oh, J.H., Falahkheirkhah, K. and Bhargava, R., “Finer Disentanglement of Aleatoric Uncertainty Can Accelerate Chemical Histopathology Imaging”. arXiv preprint arXiv:2502.20532 (2025).
Paper | DOI: 10.48550/arXiv.2502.20532

Wu, T., Thornburg, Z.R., Tan, K., Kenkel, S., Boppart, S.A., Bhargava, R. and Luthey-Schulten, Z., “Visualizing Cell Structures with Minecraft”. The Biophysicist, 6(1) (2025).
Paper | DOI: 10.35459/tbp.2024.000275

Chang, C.W., Bale, A., Bhargava, R. and Harley, B.A. “Glioblastoma Drives Protease-Independent Extracellular Matrix Invasion of Microglia” Materials Today Bio (2025).
Paper | DOI: 10.1016/j.mtbio.2025.101475

Edmonds, H., Mukherjee, S., Holcombe, B., Yeh, K., Bhargava, R. and Ghosh, A. “A Machine Learning-based Approach for Quantification of Protein Secondary Structures from Discrete Frequency Infrared Images” bioRxiv (2025).
Paper | DOI: 10.1101/2025.01.08.632028

2024

Oh, J.H., Falahkheirkhah, K. and Bhargava, R. “Detecting Hallucinations in Virtual Histology with Neural Precursors” arXiv preprint arXiv:2411.15060 (2024).
Paper | DOI: 10.48550/arXiv.2411.15060

Mukherjee, S.S., Maleszewski, J.J., Luthringer, D., Confer, M.P., Mittal, A., Dasari, S., McPhail, E.D., Kapa, S., Kesavadas, T., Kajdacsy-Balla, A., Kransdorf, E., Raman. J., and Bhargava, R. “Optical Spectroscopic Detection and Typing of Cardiac Amyloidosis” Circulation (2024).
Paper | DOI: 10.1161/CIRCULATIONAHA.124.06955

Oh, J.H., Falahkheirkhah, K. and Bhargava, R. “Are We Ready for Out-of-Distribution Detection in Digital Pathology?” In International Conference on Medical Image Computing and Computer-Assisted Intervention (2024).
Paper | DOI: 10.1007/978-3-031-72117-5_8

Salirrosas, O., Vega, E.A., Chirban, A.M., Harandi, H., Cohen, M., Anderson, A., Bhargava, R. and Conrad, C. “Laparoscopic total pancreatectomy after laparoscopic whipple”. Annals of Surgical Oncology (2024).
Paper | DOI: 10.1245/s10434-024-15576-3

Singh, D.K., Cong, Z., Song, Y.J., Liu, M., Chaudhary, R., Liu, D., Wang, Y., Prasanth, R., KC, R., Lizarazo, S., Akhnoukh, M., Gholamalamdari, O., Moitra, A., Jenkins, L.M., Bhargava, R., Nelson, E.R., Bortle, K. V., Prasanth, S. G., and Prasanth, K. V. “MANCR lncRNA Modulates Cell-Cycle Progression and Metastasis by Cis-Regulation of Nuclear Rho-GEF” Molecular and cellular biology (2024).
Paper | DOI: 10.1080/10985549.2024.2383773

Peyres, S., Wang, J., Hollyfield, D., Confer, M.P., Uner, N.B., Bhargava, R., Moore, J.S. and Sankaran, M. “Plasma Electrochemistry in Non-Aqueous Solvents and Application to Organic Synthesis” Electrochemical Society Meeting Abstracts 245 (2024).
Paper | DOI: 10.1149/MA2024-01241416mtgabs

Jeong, Y., Hsieh, P.H., Phal, Y., Bhargava, R. and Irudayaraj, J. “Label-Free Monitoring of Coculture System Dynamics: Probing Probiotic and Cancer Cell Interactions via Infrared Spectroscopic Imaging” Analytical Chemistry (2024).
Paper | DOI: 10.1021/acs.analchem.4c00894

Hur, S.W., Kwon, M., Manoharaan, R., Mohammadi, M.H., Samuel, A.Z., Mulligan, M.P., Hergenrother, P.J. and Bhargava, R. “Capturing cell morphology dynamics with high temporal resolution using single-shot quantitative phase gradient imaging” Journal of biomedical optics (2024).
Paper | DOI: 10.1117/1.JBO.29.S2.S22712

Iyer, R.R., Applegate, C.C., Arogundade, O.H., Bangru, S., Berg, I.C., Emon, B., Porras-Gomez, M., Hsieh, P.H., Jeong, Y., Kim, Y., Knox, H.J., Moghaddam, A.O., Renteria, C.A., Richard, C., Santaliz-Casiano, A., Sengupta, S., Wang, J., Zambuto, S.G., Zeballos, M.A., Pool, M., Bhargava, R., and Gaskins, H.R. ” Inspiring a convergent engineering approach to measure and model the tissue microenvironment” Heliyon (2024).
Paper | DOI: 10.1016/j.heliyon.2024.e32546

Balraj, K., Ramteke, M., Mittal, S., Bhargava, R. and Rathore, A.S. “MADR-Net: multi-level attention dilated residual neural network for segmentation of medical images” Scientific Reports (2024).
Paper | DOI: s41598-024-63538-2

Lin, H., Falahkheirkhah, K., Kindratenko, V. and Bhargava, R. “INSTRAS: INfrared Spectroscopic imaging-based TRAnsformers for medical image Segmentation” Machine Learning with Applications (2024).
Paper | DOI: 10.1016/j.mlwa.2024.100549

Sivaguru, M., Mori, S., Fouke, K.W., Ajijola, O.A., Shivkumar, K., Samuel, A.Z., Bhargava, R. and Fouke, B.W. “Osteopontin stabilization and collagen containment slows amorphous calcium phosphate transformation during human aortic valve leaflet calcification” Scientific Reports (2024).
Paper | DOI: s41598-024-62962-8

Salirrosas, O., Kawahara, W., Vega, E. A., Bhargava, R., Salehi, O., and Conrad, C. “ASO Author Reflections: Lymph Node Station 16 Status—Becoming a Student of Your Patients’ Cancer” Annals of Surgical Oncology (2024).
Paper | DOI: 10.1245/s10434-024-15099-x

Kenkel, S., and Bhargava, R. “Modeling the Thermoelastic Sample Response for Subdiffraction Infrared Spectroscopic Imaging” Chemical & Biomedical Imaging (2024).
Paper | DOI: 10.1021/cbmi.4c00018

Confer, M.P., Falahkheirkhah, K., Surendran, S., Sunny, S.P., Yeh, K., Liu, Y.T., Sharma, I., Orr, A.C., Lebovic, I., Magner, W.J., Sigurdson, S.L., Aguirre, A., Markiewicz, M.R., Suresh, A., Hicks, W.L., Birur, P., Kuriakose, M.A., and Bhargava, R. “Rapid and Label-Free Histopathology of Oral Lesions Using Deep Learning Applied to Optical and Infrared Spectroscopic Imaging Data” Journal of Personalized Medicine (2024).
Paper | DOI: 10.3390/jpm14030304

Bale, A. A., Bhargava, R., and Harley, B. “Abstract B052: Hyaluronic acid influences amino acid metabolism in glioblastoma’s U87-MG cell line in a 2D culture via LAT1 transporter expression” Cancer Research (2024).
Paper | DOI: 10.1158/1538-7445.BRAIN23-B052

Chen, J., Laverty, D.J., Talele, S., Bale, A., Carlson, B.L., Porath, K.A., Bakken, K.K., Burgenske, D.M., Decker, P.A., Vaubel, R.A., Eckel-Passow, J.E., Bhargava, R., Lou, Z., Hamerlik, P., Harley, B., Elmquist, W.F., Nagel, Z.D., Gupta, S.K., and Sarkaria, J.N. “Aberrant ATM signaling and homology-directed DNA repair as a vulnerability of p53-mutant GBM to AZD1390-mediated radiosensitization” Science translational medicine (2024).
Paper | DOI: 10.1126/scitranslmed.adj5962

Ran, J., El-Kebir, H., Lee, Y., Chamorro, L.P., Berlin, R., Aguiluz Cornejo, G.M., Benedetti, E., Giulianotti, P.C., Bhargava, R., Bentsman, J. and Ostoja-Starzewski, M. “Heat conduction in live tissue during radiofrequency electrosurgery” Journal of the Royal Society Interface (2024).
Paper | DOI: 10.1098/rsif.2023.0420

Bale, A. A., Thammineni, S., Bhargava, R., and Harley, B. “Hyaluronic Acid Influences Amino Acid Metabolism via Differential L‐Type Amino Acid Transporter 1 Expression in the U87‐Malignant Glioma Cell Line” Advanced NanoBiomed Research (2024).
Paper | DOI: 10.1002/anbr.202400107

Siddiqui, A. R., N’Diaye, J., Santiago-Carboney, A., Martin, K., Bhargava, R., and Rodríguez-López, J. “Spectroelectrochemical determination of thiolate self-assembled monolayer adsorptive stability in aqueous and non-aqueous electrolytes” Analyst (2024).
Paper | DOI: 10.1039/D4AN00241E