2006 – 2010


B.J. Davis, P.S. Carney, R. Bhargava “Theory of mid-infrared absorption microspectroscopy. II. Heterogeneous samples” Anal. Chem. 82, 3487–3499 (2010).
Paper | DOI: 10.1021/ac902068e

B.J. Davis, P.S. Carney, R. Bhargava “Theory of mid-infrared absorption microspectroscopy. I. Homogeneous samples” Anal. Chem. 82, 3474–3486 (2010).
Paper | DOI: 10.1021/ac902067p

A.K. Kodali, X. Llora, R. Bhargava “Optimally designed nanolayered metal-dielectric particles as probes for massively multiplexed and ultrasensitive molecular assays” Proc. Natl. Acad. Sci. U.S.A. 107, 13620–13625 (2010).
Paper | DOI: 10.1073/pnas.1003926107

A.K. Kodali, M. Schulmerich, J. Ip, G. Yen, B.T. Cunningham, R. Bhargava “Narrowband midinfrared reflectance filters using guided mode resonance” Anal. Chem. 82, 5697–5706 (2010).
Paper | DOI: 10.1021/ac1007128

A.K. Kodali, M. V. Schulmerich, R. Palekar, X. Llora, R. Bhargava  “Optimized nanospherical layered alternating metal-dielectric probes for optical sensing” Opt. Exp. 18, 23302–23313 (2010).
Paper | DOI: 10.1364/OE.18.023302

R. Kong, R.K. Reddy, R. Bhargava “Characterization of tumor progression in engineered tissue using infrared spectroscopic imaging” Analyst 135, 1569–1578 (2010).
Paper | DOI: 10.1039/c0an00112k

J.G. Moreno-Torres, X. Llorà, D.E. Goldberg, R. Bhargava “On the homogenization of data from two laboratories using genetic programming” Lec. Notes Comp. Sci. 6471, 185–197 (2010).
Paper | DOI: 10.1007/978-3-642-17508-4_12

R.K. Reddy, R. Bhargava “Accurate histopathology from low signal-to-noise ratio spectroscopic imaging data” Analyst 135, 2818–2825 (2010).
Paper | DOI: 10.1039/C0AN00350F

M.V. Schulmerich, R. Reddy, A.K. Kodali, L.J. Elgass, K. Tangella, R. Bhargava “Dark field Raman microscopy” Anal. Chem. 82, 6273–6280 (2010).
Paper | DOI: 10.1021/ac1014194

A.K. Kodali, R. Bhargava “Nanostructured probes to enhance optical and vibrational spectroscopic imaging for biomedical applications” The Oxford Handbook of Nanoscience and Technology: Vol. III: Applications, Y.Y. Fu, A. Narlikar, eds., Oxford University Press, Oxford, UK (2010) [Book Chapter]
ISBN: 978-01-995-3306-0

F.N. Pounder, R. Bhargava “Toward automated breast histopathology using mid-IR spectroscopic imaging” Vibrational Spectroscopic Imaging for Biomedical Applications, G. Srinivasan, ed., McGraw-Hill, New York, NY (2010) [Book Chapter]
ISBN: 978-00-715-9699-2

R.K. Reddy, R. Bhargava “Chemometric methods for biomedical Raman spectroscopy and imaging” Emerging Raman Applications and Techniques in Biomedical and Pharmaceutical Fields, M. D. Morris, P. Matousek, eds., Springer-Verlag, Berlin, Germany (2010) [Book Chapter]
DOI: 10.1007/978-3-642-02649-2_8

M.J. Walsh, R. Bhargava “Infrared spectroscopic imaging: An integrative approach to pathology” Nanobiophotonics, G. Popescu, ed., McGraw-Hill, New York, NY (2010.) [Book Chapter]
ISBN: 978-00-717-3701-2

B. Kwon, W.P. King, M.V. Schulmerich, R. Bhargava “Infrared imaging spectrometry in an atomic force microscope” Materials Research Society Fall Meeting (2010). [Conference Paper]

M.J. Walsh, M.J. Nasse, F.N. Pounder, V. Macias, A. Kajdacsy-Balla, C. Hirschmugl, R. Bhargava “Synchrotron FTIR imaging for the identification of cell types within human tissues” AIP Conference Proc. Vol. 1214 WIRMS 2009 5th International Workshop on Infrared Microscopy and Spectroscopy with Accelerator Based Sources, pp. 105–107 (2010). [Conference Paper]


R. Bhargava, R.S. Perlman, D.C. Fernandez, I.W. Levin, E. G. Bartick “Non-invasive detection of superimposed latent fingerprints and inter-ridge trace evidence by infrared spectroscopic imaging” Anal. Bioanal. Chem. 394, 2069–2075 (2009).
Paper | DOI: 10.1007/s00216-009-2817-6

X. Llorà, A. Priya, R. Bhargava “Observer-invariant histopathology using genetics-based machine learning” Nat. Computing 8, 101–120 (2009). Paper | DOI: 10.1007/s11047-007-9056-6

R. Bhargava, B. J. Davis “Histologic models for optical tomography and spectroscopy of tissues” Proc. SPIE 7174, 71742H (2009). [Conference Paper]

F.N. Pounder, R. Bhargava “Spectral histology of breast tissue using mid-infrared spectroscopic imaging” Proc. SPIE 7182, art. no. 718206 (2009). [Conference Paper]

F.N. Pounder, R.K. Reddy, M.J. Walsh, R. Bhargava “Validating the cancer diagnosis potential of mid-infrared spectroscopic imaging” Proc. SPIE 7186, art. no. 71860F (2009). [Conference Paper]


K. Park, J. Lee, R. Bhargava, W.P. King “Routine femtogram-level chemical analyses using vibrational spectroscopy and self-cleaning scanning probe microscopy tips” Anal. Chem. 80, 3221–3228 (2008).
Paper | DOI: 10.1021/ac702423c

R. Bhargava, I.W. Levin “Infrared spectroscopic imaging protocols for high-throughput histopathology” Vibrational Spectroscopy for Medical Diagnosis, M. Diem, P.R. Griffiths, J. Chalmers, eds., John Wiley and Sons, Chichester, UK (2008) [Book Chapter]
ISBN: 978-0-470-01214-7

R. Bhargava, R. Kong “Structural and biochemical characterization of engineered tissue using FTIR spectroscopic imaging: melanoma progression as an example [Design and Performance Validation of Phantoms Used in Conjunction with Optical Measurements of Tissue, R. J. Nordstrom, ed.]” Proc. SPIE 6870, 687004-1-10 (2008). [Conference Paper]

F.N. Keith, R.K. Reddy, R. Bhargava “Practical protocols for fast histopathology by Fourier transform infrared spectroscopic imaging [Biomedical Optical Spectroscopy, A. Mahadevan-Jansen, W. Petrich, R.R. Alfano, A. Katz, eds.]” Proc. SPIE 6853, 685306-1-10 (2008). [Conference Paper]

A.K. Kodali, R. Bhargava “Tunable multilayered nanospheres as probes for surface-enhanced Raman spectroscopy” [Nanoplasmonic Sensing Including SERS, M.I. Stockman, ed.]” Proc. SPIE 7032, 70320V (2008). [Conference Paper]


R. Bhargava “Towards a practical Fourier transform infrared chemical imaging protocol for cancer histopathology” Anal. Bioanal. Chem. 389, 1155–1169 (2007).
Paper | DOI: 10.1007/s00216-007-1511-9

R. Bhargava, S.M. Hewitt, I.W. Levin “Reply to Unrealistic expectations for IR microspectroscopic imaging” Nat. Biotechnol. 25,  31–33 (2007).
Paper | DOI: 10.1038/nbt0107-31

G. Srinivasan, R. Bhargava “Fourier transform infrared spectroscopic imaging: The emerging evolution from a microscopy tool to a cancer imaging modality” Spectroscopy  22, 30–43 (2007).

X. Llorà, R. Reddy, B. Matesic, R. Bhargava “Towards better than human capability in diagnosing prostate cancer using infrared spectroscopic imaging” Genetic and Evolutionary Computation Conference (GECCO) (2007). [Conference Paper]


R. Bhargava, D.C. Fernandez, S.M. Hewitt, I.W. Levin “High throughput assessment of cells and tissues: Bayesian classification of spectral metrics from infrared vibrational spectroscopic imaging data” Biochim. Biophys. Acta 1758, 830–845 (2006).
Paper | DOI: 10.1016/j.bbamem.2006.05.007

F.N. Keith, R. Kong, A. Pryia, R. Bhargava “Data processing for tissue histopathology using Fourier transform infrared spectral data” Proceedings of the 40th Asilomar Conference on Signals, Systems and Computers, IEEE (2006). [Conference Paper]